Clinical Practice Guidelines

SIO is pleased to provide its updated clinical practice guidelines for breast cancer. In June 2018, ASCO announced endorsement of the guidelines. The guidelines were published in 2017. Researchers analyzed which integrative treatments are most effective and safe for patients with breast cancer. The guidelines are a resource for clinicians and patients to inform evidence-based decisions on the use of integrative therapies during breast cancer treatment. Researchers at US and Canadian institutions evaluated the efficacy and safety of more than 80 therapies.

The Journal of the National Cancer Institute Monograph has  published a special issue co-sponsored by SIO, "Advancing the Global Impact of Integrative Oncology"; including a comprehensive definition for integrative oncology. The articles in the special Monograph were all peer-reviewed.

 JACM Announces Call for Submissions (Read more)


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SIO 2019 Conference

Standard Registration for the 16th International Conference, October 19-21, 2019 in New York, NY, is open and will remain so until 11:59 pm (ET) October 15, 2019. Don't wait to register! The conference theme is: Advancing the Science and Art of Integrative Oncology. Register here. Hotel Room Blocks are NO LONGER AVAILABLE. However, the hotel may have rooms available at non-conference rates. Please contact them directly: 212-586-7000 or visit their website.

View a list of restaurants near the Hilton Midtown.

As part of the conference, MSKCC will host two tours of its Bendheim Integrative Medicine Center on Saturday morning, October 19, beginning at 10:00 am and 10:30 am. Each tour will be limited to15-20 people per time slot. To ensure your place on a tour, sign up in advance and to get easy directions to the facility using the subway.

SIO 2019 Conference Educational Sponsor


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Duncan M; Moschopoulou E; Herrington E; Deane J; Roylance R; Jones L; Bourke L; Morgan A; Chalder T; Thaha MA; Taylor SC; Korszun A; White PD; Bhui K; SURECAN Investigators.


Review of systematic reviews of non-pharmacological interventions to improve quality of life in cancer survivors.


BMJ Open. 7(11):e015860, 2017 Nov 28.


OBJECTIVES: Over two million people in the UK are living with and beyond cancer. A third report diminished quality of life.

DESIGN: A review of published systematic reviews to identify effective non-pharmacological interventions to improve the quality of life of cancer survivors.

DATA SOURCES: Databases searched until May 2017 included PubMed, Cochrane Central, EMBASE, MEDLINE, Web of Science, the Cumulative Index to Nursing and Allied Health Literature, and PsycINFO.

STUDY SELECTION: Published systematic reviews of randomised trials of non-pharmacological interventions for people living with and beyond cancer were included; included reviews targeted patients aged over 18. All participants had already received a cancer diagnosis. Interventions located in any healthcare setting, home or online were included. Reviews of alternative therapies or those non-English reports were excluded. Two researchers independently assessed titles, abstracts and the full text of papers, and independently extracted the data.

OUTCOMES: The primary outcome of interest was any measure of global (overall) quality of life.

ANALYTICAL METHODS: Quality assessment assessing methdological quality of systematic reviews (AMSTAR) and narrative synthesis, evaluating effectiveness of non-pharmacological interventions and their components.

RESULTS: Of 14430 unique titles, 21 were included in the review of reviews. There was little overlap in the primary papers across these reviews. Thirteen reviews covered mixed tumour groups, seven focused on breast cancer and one focused on prostate cancer. Face-to-face interventions were often combined with online, telephone and paper-based reading materials. Interventions included physical, psychological or behavioural, multidimensional rehabilitation and online approaches. Yoga specifically, physical exercise more generally, cognitive behavioural therapy (CBT) and mindfulness-based stress reduction (MBSR) programmes showed benefit in terms of quality of life.

CONCLUSIONS: Exercise-based interventions were effective in the short (less than 3-8 months) and long term. CBT and MBSR also showed benefits, especially in the short term. The evidence for multidisciplinary, online and educational interventions was equivocal.Copyright © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.




Cutshall SM; Mahapatra S; Hynes RS; Van Rooy KM; Looker SA; Ghosh A; Schleck CD; Bauer BA; Wahner-Roedler DL.


Hand Massage for Cancer Patients Undergoing Chemotherapy as Outpatients: A Pilot Study.


Explore: The Journal of Science & Healing. 13(6):393-399, 2017 Nov - Dec.


CONTEXT: There are no studies on the effect of volunteer-provided hand massage in a busy chemotherapy outpatient practice.

OBJECTIVE: To assess the feasibility of introducing hand massage therapy into an outpatient chemotherapy unit and to evaluate the effect of the therapy on various symptoms experienced by cancer patients.

DESIGN: A pilot, quasi-experimental, pretest-posttest study.

SETTING: Chemotherapy outpatient clinic of a large tertiary care academic medical center.

PATIENTS/PARTICIPANTS: Forty chemotherapy outpatients.

INTERVENTION: After being approached by a trained volunteer from a hand massage team, patients consented to receive a 20-minute hand massage before chemotherapy that was individualized according to patient preference and expressed needs.

MAIN OUTCOME MEASURES: The visual analog scale (VAS) was used to measure pain, fatigue, anxiety, muscular discomfort, nervousness, stress, happiness, energy, relaxation, calmness, and emotional well-being (on a scale from 0-10) before and after the intervention; a satisfaction survey was administered after the therapy. Patients' demographic data were summarized with descriptive statistics, and VAS total scores were compared between groups at each time point with the two-group t test. Feasibility was evaluated from the number of patients who were approached, received a hand massage, and completed the study surveys.

RESULTS: Of the 40 participants, 19 were men (mean age, 59.5 years). Significant improvement after hand massage was indicated by VAS scores for fatigue, anxiety, muscular discomfort, nervousness, stress, happiness, energy, relaxation, calmness, and emotional well-being (P < .05). Pain scores also improved, but the difference was not statistically significant (P = .06). All patients indicated that they would recommend hand massage to other patients, and 37 were interested in receiving it during their next chemotherapy treatment.




Shin J; Park H.


Effects of Auricular Acupressure on Constipation in Patients With Breast Cancer Receiving Chemotherapy: A Randomized Control Trial.


Western Journal of Nursing Research. 40(1):67-83, 2018 Jan.


The purpose was to examine the effects of auricular acupressure to relieve constipation in patients with breast cancer who were undergoing chemotherapy. Participants were 52 patients with breast cancer receiving chemotherapy at E University Hospital, Seoul, Korea, randomized into two groups of equal size. For the experimental group, auricular acupressure was applied to seven auricular acupoints for 6 weeks using vaccaria seeds, whereas the control group received the usual care. Constipation-assessment scores of the experimental group were significantly lower compared with the control group ( p < .001). Stool-form scores of the experimental group were significantly higher compared with the control group ( p = .003). Patient Assessment of Constipation-Quality of Life scores of the experimental group were significantly lower compared with the control group ( p < .001). Auricular acupressure was effective at relieving constipation in patients with breast cancer receiving chemotherapy. Auricular acupressure was also a safe and acceptable nursing intervention.



  • Some #SIO2019 Int'l attendees, Patient Advocates, Moderators & Presenters, & New Investigators.…

  • @Integrativeonc photos from #SIO2019 Day 1 - early morning pre-conference workshops - stretching and getting ready…

  • Photos from #SIO2019 Day One